SubtiBank SubtiBank
yknW [2020-04-24 15:38:16]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

yknW [2020-04-24 15:38:16]

modulates assembly of the YknX-YknY-YknZ ABC transporter for the export of the SdpC toxin
locus
BSU_14340
pI
6.94
mw
24.03 kDa
protein length
231 aa Sequence Blast
gene length
696 bp Sequence Blast
function
resistence against SdpC toxin
product
modulator of ABC transporter assembly
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,503,582 1,504,277

    The protein

    [SW|Localization]

  • cell membrane (according to UniProt), membrane [Pubmed|18763711]

    • Expression and Regulation

    Operons

    genes
    [gene|70D7098BEBD5E53B4B9B8C3394FAAF972C65EE22|yknU]-[gene|C6B0ACB9D9703DD8141FD7D9D62DB22FB48F458B|yknV]-[gene|916419C4ED113778488EBC558A35810498028B02|yknW]-[gene|FD270195901B89DAAAD134DB9DE729670A9BDECF|yknX]-[gene|FE3A01BEA974C5E32C68DC600C800E5EF101B34F|yknY]-[gene|9680326BAA94A503E2A5C6F0A2479AE0B0467B4C|yknZ]
    description
    [Pubmed|22383849]
    view in new tab

    genes
    [gene|916419C4ED113778488EBC558A35810498028B02|yknW]-[gene|FD270195901B89DAAAD134DB9DE729670A9BDECF|yknX]-[gene|FE3A01BEA974C5E32C68DC600C800E5EF101B34F|yknY]-[gene|9680326BAA94A503E2A5C6F0A2479AE0B0467B4C|yknZ]
    description
    [Pubmed|9987136]

    sigma factors

  • [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]: sigma factor, [Pubmed|9987136], in [regulon|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW regulon]

    • regulatory mechanism

  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|12076816], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • regulation

  • repressed during logrithmic growth ([protein|search|AbrB]) [Pubmed|12076816]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B348 (yknW::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1347 NBRP B. subtilis, Japan]
  • BKE14340 ([gene|916419C4ED113778488EBC558A35810498028B02|yknW]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCAAAACCTCCTTGAG, downstream forward: _UP4_AATTCTGTGGCGGGTGCATA
  • BKK14340 ([gene|916419C4ED113778488EBC558A35810498028B02|yknW]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK14340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCAAAACCTCCTTGAG, downstream forward: _UP4_AATTCTGTGGCGGGTGCATA

    • References

  • 16629676,12076816,18763711,9987136